CP-664511 is a potent α4β1 integrin antagonist with an IC50 of 0.52 nM, exhibiting significant anti-inflammatory properties. By inhibiting the interaction between α4β1 integrin and vascular cell adhesion molecule-1 (VCAM-1), CP-664511 effectively reduces eosinophil infiltration into lung tissue. This compound is valuable for investigating mechanisms underlying asthma and allergic airway diseases.
CP-664511 is a potent α4β1 integrin antagonist with an IC50 of 0.52 nM, exhibiting significant anti-inflammatory properties. By inhibiting the interaction between α4β1 integrin and vascular cell adhesion molecule-1 (VCAM-1), CP-664511 effectively reduces eosinophil infiltration into lung tissue. This compound is valuable for investigating mechanisms underlying asthma and allergic airway diseases.
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