CPI-203-PEG1-C3-O-COOH

Catalog No.: A40462
BRD4 Ligand-Linker Conjugate
CPI-203-PEG1-C3-O-COOH is a BRD4 ligand-linker conjugate, designed to facilitate the synthesis of PROTAC (proteolysis-targeting chimera) molecules, specifically the BRD4 degrader ARV-771. This compound serves as a crucial component in targeted protein degradation research, enabling the selective modulation of BRD4 protein levels and aiding in the understanding of its biological functions. Its application is significant in therapeutic development for diseases associated with dysregulated BRD4 activity.
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5mg
10mg
50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCPI-203-PEG1-C3-O-COOH is a BRD4 ligand-linker conjugate, designed to facilitate the synthesis of PROTAC (proteolysis-targeting chimera) molecules, specifically the BRD4 degrader ARV-771. This compound serves as a crucial component in targeted protein degradation research, enabling the selective modulation of BRD4 protein levels and aiding in the understanding of its biological functions. Its application is significant in therapeutic development for diseases associated with dysregulated BRD4 activity.
Product Information
Catalog NumA40462
FormulaC26H30ClN5O5S
Molecular Weight560.06
CAS Number1997304-12-7
SMILESCC1=C(C)C(C(C2=CC=C(Cl)C=C2)=N[C@@H](CC(NCCOCCCOCC(O)=O)=O)C3=NN=C(C)N34)=C4S1
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