CPI-613

Catalog No.: A11786

Dehydrogenase Inhibitor

CPI-613

CPI-613 Chemical Structure

CAS NO. 95809-78-2

CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$65.00
25 mg
$90.00
50 mg
$140.00
10mM * 1mL in DMSO
$50.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Egawa Y, .et al. Therapeutic potential of CPI-613 for targeting tumorous mitochondrial energy metabolism and inhibiting autophagy in clear cell sarcoma, PLoS One, 2018, Jun 7;13(6):e0198940 PMID: 29879220

Biological Activity

CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities.
Targets
PDH (NCI-H460 cells) α-ketoglutarate dehydrogenase (NCI-H460 cells)
In vitro (25°C) DMSO 78 mg/mL (200.72 mM)
Water <1 mg/mL (<1 mM)
Ethanol 78 mg/mL (200.72 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.73 mL 128.67 mL 257.33 mL
0.5 mM 5.15 mL 25.73 mL 51.47 mL
1 mM 2.57 mL 12.87 mL 25.73 mL
5 mM 0.51 mL 2.57 mL 5.15 mL

*The above data is based on the productmolecular weight 388.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11786
Actions Inhibitor
M. Wt 388.6
Formula C22H28O2S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 95809-78-2
Synonyms CPI613
SMILES C1=CC=C(C=C1)CSCCC(CCCCC(=O)O)SCC2=CC=CC=C2

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