CRTh2 antagonist 4

Catalog No.: A63218
DP2 Receptor Inhibitor
CRTh2 antagonist 4 is a selective inhibitor of the DP2 receptor, displaying an IC50 value of 212 nM and a binding affinity with a Ki of 37 nM. This compound is useful in the investigation of TH2 lymphocyte-related pathways and has potential applications in understanding and treating severe allergic diseases.
Grouped product items
Size Price Stock Qty
1mg
$125.00
In stock
5mg
$575.00
In stock
10mg
$1,645.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
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Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCRTh2 antagonist 4 is a selective inhibitor of the DP2 receptor, displaying an IC50 value of 212 nM and a binding affinity with a Ki of 37 nM. This compound is useful in the investigation of TH2 lymphocyte-related pathways and has potential applications in understanding and treating severe allergic diseases.
Product Information
Catalog NumA63218
FormulaC20H14ClFN2O5
Molecular Weight416.79
CAS Number916046-55-4
SMILESO=C(O)CN1C(C2(C(N(CC3=CC=CC=C3F)C(C2)=O)=O)C4=C1C=CC(Cl)=C4)=O
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