CS12192

Catalog No.: A33348
JAK3/JAK1/TBK1 Inhibitor
CS12192 is a JAK3/JAK1/TBK1 inhibitor that modulates immune responses by inhibiting key signaling pathways involved in inflammatory processes. This compound has demonstrated efficacy in improving survival and promoting weight gain. CS12192 holds potential for research applications in graft-versus-host disease (GVHD), offering insights into therapeutic strategies for managing this condition.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCS12192 is a JAK3/JAK1/TBK1 inhibitor that modulates immune responses by inhibiting key signaling pathways involved in inflammatory processes. This compound has demonstrated efficacy in improving survival and promoting weight gain. CS12192 holds potential for research applications in graft-versus-host disease (GVHD), offering insights into therapeutic strategies for managing this condition.
Product Information
Catalog NumA33348
FormulaC25H23ClFN7O2
Molecular Weight507.95
CAS Number1888318-68-0
SMILESN#CC1=CC=C(C(NCCCNC2=NC(NC3=CC=C(C(N(C)C(C=C)=O)=C3)F)=NC=C2Cl)=O)C=C1
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