CVT-12012

Catalog No.: A21447

SCD inhibitor

CVT-12012

CVT-12012 Chemical Structure

CAS NO. 1018675-35-8

CVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM, 6.1 nM for rat microsomal and human HEPG2, respectively.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$155.00
50 mg
$460.00
100 mg
$920.00
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Biological Activity

CVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM, 6.1 nM for rat microsomal and human HEPG2, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.02 mL 115.1 mL 230.2 mL
0.5 mM 4.6 mL 23.02 mL 46.04 mL
1 mM 2.3 mL 11.51 mL 23.02 mL
5 mM 0.46 mL 2.3 mL 4.6 mL

*The above data is based on the productmolecular weight 434.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21447
Actions Inhibitor
M. Wt 434.41
Formula C21H21F3N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1018675-35-8
Synonyms CVT12012, CVT 12012
SMILES O=C(NCCN1C(C(C)=NC2=C1C=C(NCC3=CC=CC(C(F)(F)F)=C3)C=C2)=O)CO

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