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Cyclosporin C is a highly lipophilic cyclic peptide natural product, a member of the cyclosporin series of antifungal and immunosuppresive compounds - Cyclosporin A and B. The cyclosporins bind the cyclophilin intracellular proteins, highly conserved proteins involved in cis-trans isomerization of peptidyl-prolyl bonds and protein folding.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 8.21 mL | 41.03 mL | 82.06 mL |
| 0.5 mM | 1.64 mL | 8.21 mL | 16.41 mL |
| 1 mM | 0.82 mL | 4.1 mL | 8.21 mL |
| 5 mM | 0.16 mL | 0.82 mL | 1.64 mL |
*The above data is based on the productmolecular weight 1218.61. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13792 |
|---|---|
| M. Wt | 1218.61 |
| Formula | C62H111N11O13 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 59787-61-0 |
| Synonyms | Thr2-cyclosporine, WF-3484 |
| SMILES | CC=CCC(C)C(C1C(=O)NC(C(=O)N(CC(=O)N(C(C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)CC(C)C)C)C(C)C)CC(C)C)C)C)C(C)O)O |
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