CysLT1 receptor antagonist-1 is a selective antagonist of the cysteinyl leukotriene receptor 1 (CysLT1R), exhibiting an IC50 value of 3.9 µM. This compound demonstrates weak agonistic activity against the G-protein-coupled bile acid receptor 1 (GPBAR1) with an efficacy of 23% at 10 µM. CysLT1 receptor antagonist-1 is primarily utilized in research related to asthma and allergic diseases, aiding in the exploration of therapeutic interventions targeting these conditions.
CysLT1 receptor antagonist-1 is a selective antagonist of the cysteinyl leukotriene receptor 1 (CysLT1R), exhibiting an IC50 value of 3.9 µM. This compound demonstrates weak agonistic activity against the G-protein-coupled bile acid receptor 1 (GPBAR1) with an efficacy of 23% at 10 µM. CysLT1 receptor antagonist-1 is primarily utilized in research related to asthma and allergic diseases, aiding in the exploration of therapeutic interventions targeting these conditions.
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