Cytisine-d4

Catalog No.: A67703
Stable Isotope
Cytisine-d4 is a deuterium-labeled derivative of Cytisinicline, an alkaloid known for its role as a partial agonist at α4β2 nicotinic acetylcholine receptors (nAChRs) and for displaying full to partial agonism at β4-containing and α7 receptors. This stable isotope is utilized in research applications aimed at studying receptor interactions and pharmacokinetics, as well as in investigations related to smoking cessation therapies. The incorporation of deuterium allows for enhanced tracking of metabolic pathways and biological activity in various experimental settings.
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5mg
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50mg
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCytisine-d4 is a deuterium-labeled derivative of Cytisinicline, an alkaloid known for its role as a partial agonist at α4β2 nicotinic acetylcholine receptors (nAChRs) and for displaying full to partial agonism at β4-containing and α7 receptors. This stable isotope is utilized in research applications aimed at studying receptor interactions and pharmacokinetics, as well as in investigations related to smoking cessation therapies. The incorporation of deuterium allows for enhanced tracking of metabolic pathways and biological activity in various experimental settings.
Product Information
Catalog NumA67703
FormulaC11H10D4N2O
Molecular Weight194.27
CAS Number2714473-76-2
SMILESO=C1N2C[C@@]3(C([2H])(NC([2H])([C@]([H])(C2=CC=C1)C3)[2H])[2H])[H]
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