Cytochalasin J is a cytochalasin derivative that targets microtubule organization. It disrupts mitotic spindle formation and alters kinetochore structure, demonstrating cytotoxic effects in human leukemia K562 cells with an IC50 of 1.5 μM. This compound is valuable for research applications in cancer biology, particularly in the study of cell division and cancer cell dynamics.
Cytochalasin J is a cytochalasin derivative that targets microtubule organization. It disrupts mitotic spindle formation and alters kinetochore structure, demonstrating cytotoxic effects in human leukemia K562 cells with an IC50 of 1.5 μM. This compound is valuable for research applications in cancer biology, particularly in the study of cell division and cancer cell dynamics.
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