Gap Junction Protein

Tonabersat is a novel benzopyran derivative that blocks the cortical spreading depression proposed to be associated with migraine attacks.

Gap 26 is a connexin mimetic peptide, corresponding to residues 63-75 of connexin 43, which is a gap junction blocker.

Gap 27 is a peptide derived from connexin 43 that is a selective gap junction blocker.

N/A

10Panx, Panx-1 mimetic inhibitory peptide, is a blocker of pannexin-1 gap junctions.

Scrambled 10Panx, Panx-1 mimetic inhibitory peptide, is a blocker of pannexin-1 gap junctions.

GAP-134 , a small modified dipeptide, has been identified as a potent and selective second generation gap junction modifier with oral bioavailability.

GAP-134 Hydrochloride, a small modified dipeptide, has been identified as a potent and selective second generation gap junction modifier with oral bioavailability.

AT-1002, a 6-mer synthetic peptide, is a tight junction regulator and absorption enhancer.