Integrin

CLT-28643 is an integrin α5β1 inhibitor that plays a significant role in modulating cellular adhesion and migration. It effectively reduces the overexpression of integrin α5β1 in post-surgical blebs, thereby facilitating the wound healing process. This compound is valuable for research in tissue regeneration and healing mechanisms.

RUC-1 is a specific inhibitor of the αIIbβ3 integrin. This compound effectively inhibits fibrin deposition and platelet aggregation in mouse models expressing hybrid hαIIb/mβ3 receptors. RUC-1 demonstrates significant antithrombotic effects, making it a valuable tool for studying integrin-related processes and potential therapeutic applications in coagulation disorders.