CZC24832

Catalog No.: A11363
PI3K inhibitor
CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).
Grouped product items
Product Name Price Stock Qty
CZC24832 5mg
Special Price $64.00 Regular Price $80.00
In stock
CZC24832 10mg
Special Price $112.00 Regular Price $140.00
In stock
CZC24832 25mg
Special Price $224.00 Regular Price $280.00
In stock
CZC24832 50mg
Special Price $384.00 Regular Price $480.00
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Adooq Products cited in reputable paper
Adooq's CZC24832 has been cited by 1 publications
  • Yoshihiro Umezawa, .et al. , J Biol Chem, 2017, Dec 1; 292(48): 19639-19655 PMID: 28974577
  • Biological Activity
    Discription CZC24832 is a selective inhibitor of PI 3-Kinase γ (IC50 = 1.0 μM in a PI 3-Kγ-dependent fMLP-induced neutrophil migration assay).
    Targets
    Target Value
    Product Information
    Catalog Num A11363
    Formula C15H17FN6O2S
    Molecular Weight 364.4
    CAS Number 1159824-67-5
    SMILES CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F
    Synonyms CZC 24832, CZC-24832
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO Warmed: 5 mg/mL (13.72 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 0.5% CMC 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.44 mL 137.21 mL 274.42 mL
    0.5 mM 5.49 mL 27.44 mL 54.88 mL
    1 mM 2.74 mL 13.72 mL 27.44 mL
    5 mM 0.55 mL 2.74 mL 5.49 mL
    Useful Calculator

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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