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D4476 is a cell-permeant inhibitor of casein kinase 1.
Targets
| CK1 from Schizosaccharomyces pombe | CK1δ | ALK5 | ||
| 200 nM | 300 nM | 500 nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.1 mL | 125.5 mL | 251 mL |
| 0.5 mM | 5.02 mL | 25.1 mL | 50.2 mL |
| 1 mM | 2.51 mL | 12.55 mL | 25.1 mL |
| 5 mM | 0.5 mL | 2.51 mL | 5.02 mL |
*The above data is based on the productmolecular weight 398.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13949 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 398.41 |
| Formula | C23H18N4O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 301836-43-1 |
| Synonyms | D 4476, D-4476 |
| SMILES | C1COC2=C(O1)C=CC(=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5 |
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