Catalog No.: A13949

CK1 Inhibitor


D4476 Chemical Structure

CAS NO. 301836-43-1

D4476 is a cell-permeant inhibitor of casein kinase 1.

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Biological Activity

D4476 is a cell-permeant inhibitor of casein kinase 1.
CK1 from Schizosaccharomyces pombe CK1δ ALK5
200 nM300 nM500 nM
In vitro DMSO 71 mg/mL (178.2 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.1 mL 125.5 mL 251 mL
0.5 mM 5.02 mL 25.1 mL 50.2 mL
1 mM 2.51 mL 12.55 mL 25.1 mL
5 mM 0.5 mL 2.51 mL 5.02 mL

*The above data is based on the productmolecular weight 398.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13949
Actions Inhibitor
CAS No. 301836-43-1
Formula C23H18N4O3
M. Wt 398.41
Solubility DMSO
Purity >98%
Synonyms D 4476, D-4476

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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