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Biological Activity
LH 846 is a selective inhibitor of casein kinase (CK) 1δ (IC50 values are 290 nM, 1.3 μM and 2.5 μM for CK1δ, ε and α)
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.56 mL | 157.82 mL | 315.65 mL |
| 0.5 mM | 6.31 mL | 31.56 mL | 63.13 mL |
| 1 mM | 3.16 mL | 15.78 mL | 31.56 mL |
| 5 mM | 0.63 mL | 3.16 mL | 6.31 mL |
*The above data is based on the productmolecular weight 316.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13574 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 639052-78-1 |
| Formula | C16H13ClN2OS |
| M. Wt | 316.81 |
| Purity | >98% |
| Synonyms | LH-846, LH846 |
| SMILES | CC1=CC2=C(C=C1Cl)N=C(S2)NC(=O)CC3=CC=CC=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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