Catalog No.: A21709

mitotic/tubulin inhibitor


D8-MMAE Chemical Structure

CAS NO. 2070009-72-0

D8-MMAE (D8-Monomethyl auristatin E) is a deuterated labeled MMAE, a potent mitotic inhibitor and a tubulin inhibitor.

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Biological Activity

D8-MMAE (D8-Monomethyl auristatin E) is a deuterated labeled MMAE, a potent mitotic inhibitor and a tubulin inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.77 mL 68.87 mL 137.74 mL
0.5 mM 2.75 mL 13.77 mL 27.55 mL
1 mM 1.38 mL 6.89 mL 13.77 mL
5 mM 0.28 mL 1.38 mL 2.75 mL

*The above data is based on the productmolecular weight 726.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21709
Actions Inhibitor
CAS No. 2070009-72-0
Formula C39H59D8N5O7
M. Wt 726.03
Purity >98%
Synonyms D8-Monomethyl auristatin E
SMILES CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(N1[[email protected]@H](CCC1)[[email protected]@H]([[email protected]@H](C)C(N[[email protected]](C)[[email protected]@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([[email protected]@](C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])([2H])NC([[email protected]](C(C)C)NC)=O)=O)C

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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