Biological Activity
D8-MMAE (D8-Monomethyl auristatin E) is a deuterated labeled MMAE, a potent mitotic inhibitor and a tubulin inhibitor.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 13.77 mL | 68.87 mL | 137.74 mL |
0.5 mM | 2.75 mL | 13.77 mL | 27.55 mL |
1 mM | 1.38 mL | 6.89 mL | 13.77 mL |
5 mM | 0.28 mL | 1.38 mL | 2.75 mL |
*The above data is based on the productmolecular weight 726.03. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21709 |
---|---|
Actions | Inhibitor |
CAS No. | 2070009-72-0 |
Formula | C39H59D8N5O7 |
M. Wt | 726.03 |
Purity | >98% |
Synonyms | D8-Monomethyl auristatin E |
SMILES | CC[[email protected]](C)[[email protected]@H]([[email protected]@H](CC(N1[[email protected]@H](CCC1)[[email protected]@H]([[email protected]@H](C)C(N[[email protected]](C)[[email protected]@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([[email protected]@](C(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])([2H])NC([[email protected]](C(C)C)NC)=O)=O)C |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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