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Biological Activity
Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.
| In vitro | DMSO | 57 mg/mL (169.52 mM) | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.74 mL | 148.71 mL | 297.42 mL |
| 0.5 mM | 5.95 mL | 29.74 mL | 59.48 mL |
| 1 mM | 2.97 mL | 14.87 mL | 29.74 mL |
| 5 mM | 0.59 mL | 2.97 mL | 5.95 mL |
*The above data is based on the productmolecular weight 336.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A17644 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 14663-23-1 |
| Formula | C14H9N4NaO5 |
| M. Wt | 336.23 |
| Purity | >98% |
| Synonyms | F 440, F440, F-440 |
| SMILES | O=C([N-]1)N(/N=C/C2=CC=C(C3=CC=C([N+]([O-])=O)C=C3)O2)CC1=O.[Na+] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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