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Dapagliflozin (BMS512148)


SGLT2 inhibitor

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Catalog No. A10285

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Dapagliflozin 5mg A10285-5

Regular Price: $40.00

Special Price: $36.00

Dapagliflozin 10mg A10285-10

Regular Price: $60.00

Special Price: $54.00

Dapagliflozin 50mg A10285-50

Regular Price: $200.00

Special Price: $180.00

Dapagliflozin 100mg A10285-100

Regular Price: $350.00

Special Price: $315.00

Dapagliflozin (BMS512148) 10mM * 1mL in DMSO A10285-10mM-D

Regular Price: $141.00

Special Price: $126.90

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.

Dapagliflozin (BMS512148)

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Publications citing Adooq Products
Dapagliflozin (BMS512148) Citations (2)
  • Marina Subramaniam, .et al. Sigmoidal kinetics define porcine intestinal segregation of electrogenic monosaccharide transport systems as having multiple transporter population involvement, Physiol Rep, 2019, May; 7(9): e14090 PMID: 31062524
  • Angelopoulou A, .et al. Magnetic Nanoparticles for the Delivery of Dapagliflozin to Hypoxic Tumors: Physicochemical Characterization and Cell Studies, AAPS PharmSciTech, 2018, Feb;19(2):621-633 PMID: 8924948

Chemical Information

Catalog Num A10285
Actions Inhibitor
M. Wt 408.9
Formula C21H25ClO6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 461432-26-8
Synonyms BMS512148, BMS-512148
SMILES CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[[email protected]]3[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O3)CO)O)O)O)Cl

Biological Activity

Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.


Solubility (25°C) * In vitro DMSO 82 mg/mL (200.55 mM)
Water <1 mg/mL (<1 mM)
Ethanol 17 mg/mL (41.57 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.46 mL 122.28 mL 244.56mL
0.5 mM 4.89 mL 24.46 mL 48.91 mL
1 mM 2.45 mL 12.23 mL 24.46 mL
5 mM 0.49 mL 2.45 mL 4.89 mL

*The above data is based on the productmolecular weight 408.9 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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