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Catalog No.: A10289

DNA/RNA Synthesis inhibitor


Daptomycin Chemical Structure

CAS NO. 103060-53-3

Daptomycin is a lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms.

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Viktoria Lazar, .et al. Antibiotic combinations reduce Staphylococcus aureus clearance, Nature, 2022, 610: 540-546 PMID: 36198788
  • Shigeru Fujimura, .et al. Antimicrobial efficacy of combined clarithromycin plus daptomycin against biofilms-formed methicillin-resistant Staphylococcus aureus on titanium medical devices., J Infect Chemother., 2015, Oct;21(10):756-9 PMID: 26162777

Biological Activity

Daptomycin is a lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms.
DNA synthesis (Cell-free assay)
In vitro DMSO 87 mg/mL (53.68 mM)
Water Warmed: 87 mg/mL (53.68 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 6.17 mL 30.85 mL 61.7 mL
0.5 mM 1.23 mL 6.17 mL 12.34 mL
1 mM 0.62 mL 3.09 mL 6.17 mL
5 mM 0.12 mL 0.62 mL 1.23 mL

*The above data is based on the productmolecular weight 1620.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10289
Actions Inhibitor
CAS No. 103060-53-3
Formula C72H101N17O26
M. Wt 1620.7
Purity >98%
Synonyms Cubicin
SMILES O=C([[email protected]](CC1=CNC2=CC=CC=C12)NC(CCCCCCCCC)=O)N[[email protected]@H](C(N[[email protected]](C(N[[email protected]@H]([[email protected]@H](C)OC([[email protected]]([H])(CC(C3=C(N)C=CC=C3)=O)NC([[email protected]]([H])([[email protected]@H](CC(O)=O)C)NC([[email protected]@]([H])(CO)NC(CNC4=O)=O)=O)=O)=O)C(NCC(N[[email protected]@H](CCCN)C(N[[email protected]@]([H])(CC(O)=O)C(N[[email protected]](C)C(N[[email protected]]4CC(O)

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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