Dasatinib hydrochloride

Catalog No.: A15060

Src inhibitor

Dasatinib hydrochloride

Dasatinib hydrochloride Chemical Structure

CAS NO. 854001-07-3

Dasatinib hydrochloride is a potent and dual Abl/ Src inhibitor IC50 of <1 nM/0.8 nM respectively; also inhibit c-Kit (WT)/c-Kit (D816V) with IC50 of 79 nM/37 nM.

Availability: In stock

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50 mg

Regular Price: $120.00

Special Price $96.00

200 mg

Regular Price: $650.00

Special Price $520.00

500 mg

Regular Price: $980.00

Special Price $784.00

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Biological Activity

Dasatinib hydrochloride is a potent and dual Abl/ Src inhibitor IC50 of <1 nM/0.8 nM respectively; also inhibit c-Kit (WT)/c-Kit (D816V) with IC50 of 79 nM/37 nM.
In vitro DMSO 85 mg/mL (162.06 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.07 mL 95.33 mL 190.67 mL
0.5 mM 3.81 mL 19.07 mL 38.13 mL
1 mM 1.91 mL 9.53 mL 19.07 mL
5 mM 0.38 mL 1.91 mL 3.81 mL

*The above data is based on the productmolecular weight 524.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15060
Actions Inhibitor
CAS No. 854001-07-3
Formula C22H27Cl2N7O2S
M. Wt 524.47
Purity >98%
Synonyms BMS-354825 hydrochloride, Sprycel hydrochloride, BMS354825 hydrochloride, BMS 354825 hydrochloride
SMILES CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=NC(=NC(=C3)N4CCN(CC4)CCO)C.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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