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DBCO-HS-PEG2-VA-PABC-SG3199

Catalog No.: A37342
Drug-Linker Conjugate for ADC
DBCO-HS-PEG2-VA-PABC-SG3199 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It features a SG3199-based DNA small channel crosslinker combined with a cleavable linker, facilitating targeted delivery of therapeutic agents. This reagent is suitable for the synthesis of ADCs, enabling enhanced efficacy in drug-based cancer therapies and other biomedical research applications.
DBCO-HS-PEG2-VA-PABC-SG3199 3052634-58-6 Drug-Linker Conjugate for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDBCO-HS-PEG2-VA-PABC-SG3199 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It features a SG3199-based DNA small channel crosslinker combined with a cleavable linker, facilitating targeted delivery of therapeutic agents. This reagent is suitable for the synthesis of ADCs, enabling enhanced efficacy in drug-based cancer therapies and other biomedical research applications.
Product Information
Catalog NumA37342
FormulaC75H86N10O18S
Molecular Weight1447.61
CAS Number3052634-58-6
SMILESO=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCCC(NS(NCCOCCOCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC(C=C4)=CC=C4COC(N5C6=CC(OCCCCCOC7=C(C=C8C(N=C[C@@]9([H])N(C=C(C9)C)C8=O)=C7)OC)=C(OC)C=C6C(N%10[C@](CC(C)=C%10)([H])[C@@H]5O)=O)=O)=O)=O)=O)(=O)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC
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