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$0.00 Biological Activity
dBET1 is a potent BRD4 protein degrader based on PROTAC technology with an EC50 of 430 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.73 mL | 63.67 mL | 127.34 mL |
| 0.5 mM | 2.55 mL | 12.73 mL | 25.47 mL |
| 1 mM | 1.27 mL | 6.37 mL | 12.73 mL |
| 5 mM | 0.25 mL | 1.27 mL | 2.55 mL |
*The above data is based on the productmolecular weight 785.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16858 |
|---|---|
| Actions | Degrader |
| M. Wt | 785.27 |
| Formula | C38H37ClN8O7S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1799711-21-9 |
| Synonyms | dBET-1, dBET 1 |
| SMILES | O=C(NCCCCNC(COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O)C[[email protected]]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4 |
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