dBET57

Catalog No.: A19133
BRD4BD1degrader
dBET57 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology.
Grouped product items
Product Name Price Stock Qty
dBET57 5mg
Special Price $96.00 Regular Price $120.00
In stock
dBET57 10mg
Special Price $176.00 Regular Price $220.00
In stock
dBET57 50mg
Special Price $400.00 Regular Price $500.00
In stock
dBET57 100mg
Special Price $640.00 Regular Price $800.00
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription dBET57 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology.
Targets
Target Value
Product Information
Catalog Num A19133
Formula C34H31ClN8O5S
Molecular Weight 699.18
CAS Number 1883863-52-2
SMILES O=C(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4
Synonyms dBET 57, dBET-57
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 89 mg/mL (127.29 mM)
Water Insoluble
Ethanol 11 mg/mL (15.73 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.3 mL 71.51 mL 143.02 mL
0.5 mM 2.86 mL 14.3 mL 28.6 mL
1 mM 1.43 mL 7.15 mL 14.3 mL
5 mM 0.29 mL 1.43 mL 2.86 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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