dBET57
Catalog No.: A19133
BRD4BD1degrader
dBET57 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology.
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Biological Activity
| Description | dBET57 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology. | ||
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| Targets |
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Product Information
| Catalog Num | A19133 |
|---|---|
| Formula | C34H31ClN8O5S |
| Molecular Weight | 699.18 |
| CAS Number | 1883863-52-2 |
| SMILES | O=C(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4 |
| Synonyms | dBET 57, dBET-57 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 89 mg/mL (127.29 mM) | |
| Water | Insoluble | ||
| Ethanol | 11 mg/mL (15.73 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.3 mL | 71.51 mL | 143.02 mL |
| 0.5 mM | 2.86 mL | 14.3 mL | 28.6 mL |
| 1 mM | 1.43 mL | 7.15 mL | 14.3 mL |
| 5 mM | 0.29 mL | 1.43 mL | 2.86 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
