DBI-2 is an AMPK activator that targets mitochondrial complex I. It disrupts oxidative phosphorylation (OXPHOS), leading to a reduction in ATP generation within mitochondria. DBI-2 demonstrates significant inhibitory effects on the proliferation of colorectal cancer (CRC) cells, making it a valuable tool for investigating metabolic dysregulation in cancer research.
DBI-2 is an AMPK activator that targets mitochondrial complex I. It disrupts oxidative phosphorylation (OXPHOS), leading to a reduction in ATP generation within mitochondria. DBI-2 demonstrates significant inhibitory effects on the proliferation of colorectal cancer (CRC) cells, making it a valuable tool for investigating metabolic dysregulation in cancer research.
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