ddhCTP is a nucleoside analog that acts as a selective inhibitor of DNA polymerase. It effectively disrupts DNA synthesis with Ki values of 1.32 μM for DNA polymerase beta and 0.034 μM for DNA polymerase gamma. This compound is valuable for research applications involving the study of DNA replication and polymerase-specific pathways, providing insights into cellular mechanisms and potential therapeutic targets.
ddhCTP is a nucleoside analog that acts as a selective inhibitor of DNA polymerase. It effectively disrupts DNA synthesis with Ki values of 1.32 μM for DNA polymerase beta and 0.034 μM for DNA polymerase gamma. This compound is valuable for research applications involving the study of DNA replication and polymerase-specific pathways, providing insights into cellular mechanisms and potential therapeutic targets.
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