Dec-9-yn-1-amine

Catalog No.: A83817
PROTAC Linker
Dec-9-yn-1-amine is a versatile linker utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the effective conjugation of targeting moieties to E3 ligase recruiters, enhancing the degradation of specific proteins through targeted ubiquitination. Its application in PROTAC development makes it a valuable tool for research focused on protein degradation and disease modulation.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDec-9-yn-1-amine is a versatile linker utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the effective conjugation of targeting moieties to E3 ligase recruiters, enhancing the degradation of specific proteins through targeted ubiquitination. Its application in PROTAC development makes it a valuable tool for research focused on protein degradation and disease modulation.
Product Information
Catalog NumA83817
FormulaC10H19N
Molecular Weight153.26
CAS Number1027371-95-4
SMILESC#CCCCCCCCCN
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