Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order


Catalog No.: A14012

JAK3 inhibitor


Decernotinib Chemical Structure

CAS NO. 944842-54-0

Decernotinib is an oral, selective Janus kinase 3 (JAK3) inhibitor being developed by Vertex.

Availability: In stock

Package Price Qty
2 mg
5 mg
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Decernotinib is an oral, selective Janus kinase 3 (JAK3) inhibitor being developed by Vertex.
2.5 nM(Ki)11 nM11 nM(Ki)13 nM(Ki)13 nM(Ki)
In vitro DMSO 70 mg/mL (178.39 mM)
Water Insoluble
Ethanol Warmed: 18 mg/mL (45.87 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.49 mL 127.43 mL 254.85 mL
0.5 mM 5.1 mL 25.49 mL 50.97 mL
1 mM 2.55 mL 12.74 mL 25.49 mL
5 mM 0.51 mL 2.55 mL 5.1 mL

*The above data is based on the productmolecular weight 392.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14012
Actions Inhibitor
CAS No. 944842-54-0
Formula C18H19F3N6O
M. Wt 392.38
Purity >98%
Synonyms VX-509, VX509, VX 509, VRT-831509, VRT831509, VRT 831509
SMILES CC[[email protected]](C)(C(=O)NCC(F)(F)F)NC1=NC(=NC=C1)C2=CNC3=C2C=CC=N3

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
You may also be interested in the following product(s)
Keywords:buy Decernotinib | Decernotinib Supplier | purchase | cost | manufacturer | order | distributor | buy 944842-54-0| 944842-54-0 Supplier | purchase 944842-54-0 | 944842-54-0 cost | 944842-54-0 manufacturer | order 944842-54-0 | 944842-54-0 distributor