Decernotinib

Catalog No.: A14012
JAK3 inhibitor
Decernotinib is an oral, selective Janus kinase 3 (JAK3) inhibitor being developed by Vertex.
Grouped product items
Product Name Price Stock Qty
Decernotinib 2mg
$60.00
In stock
Decernotinib 5mg
$90.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Decernotinib is an oral, selective Janus kinase 3 (JAK3) inhibitor being developed by Vertex.
Targets
Target Value
Product Information
Catalog Num A14012
Formula C18H19F3N6O
Molecular Weight 392.38
CAS Number 944842-54-0
SMILES CC[C@](C)(C(=O)NCC(F)(F)F)NC1=NC(=NC=C1)C2=CNC3=C2C=CC=N3
Synonyms VX-509, VX509, VX 509, VRT-831509, VRT831509, VRT 831509
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 70 mg/mL (178.39 mM)
Water Insoluble
Ethanol Warmed: 18 mg/mL (45.87 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.49 mL 127.43 mL 254.85 mL
0.5 mM 5.1 mL 25.49 mL 50.97 mL
1 mM 2.55 mL 12.74 mL 25.49 mL
5 mM 0.51 mL 2.55 mL 5.1 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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