Dextromilnacipran-d6

Catalog No.: A79215
Stable Isotope
Dextromilnacipran-d6 is a deuterium-labeled analog of Dextromilnacipran, a selective serotonin and norepinephrine (5-HT/NE) reuptake inhibitor. This compound also acts as a human alpha-adrenergic receptor antagonist, exhibiting an IC50 of 3.4 μM. Dextromilnacipran-d6 is a valuable tool for metabolic and pharmacokinetic studies, providing insights into the behavior and efficacy of 5-HT/NE reuptake inhibitors in various research contexts.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDextromilnacipran-d6 is a deuterium-labeled analog of Dextromilnacipran, a selective serotonin and norepinephrine (5-HT/NE) reuptake inhibitor. This compound also acts as a human alpha-adrenergic receptor antagonist, exhibiting an IC50 of 3.4 μM. Dextromilnacipran-d6 is a valuable tool for metabolic and pharmacokinetic studies, providing insights into the behavior and efficacy of 5-HT/NE reuptake inhibitors in various research contexts.
Product Information
Catalog NumA79215
FormulaC15H17D5N2O
Molecular Weight251.38
CAS Number1127352-73-1
SMILESCCN(CC)C([C@@]1(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])[C@H](C1)CN)=O
Synonyms(1R,2S)-Milnacipran-d6; F2696-d6
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