Di-tert-butyl adipate

Catalog No.: A84124
PROTAC Linker
Di-tert-butyl adipate is a linker specifically utilized in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the formation of bifunctional small molecules that promote targeted protein degradation. Its key applications include drug discovery and development, particularly in biochemistry and cellular biology research involving protein homeostasis and regulation.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDi-tert-butyl adipate is a linker specifically utilized in the synthesis of PROTAC (Proteolysis Targeting Chimeras) molecules. This compound facilitates the formation of bifunctional small molecules that promote targeted protein degradation. Its key applications include drug discovery and development, particularly in biochemistry and cellular biology research involving protein homeostasis and regulation.
Product Information
Catalog NumA84124
FormulaC14H26O4
Molecular Weight258.36
CAS Number20270-53-5
SMILESO=C(OC(C)(C)C)CCCCC(=O)OC(C)(C)C
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