diABZI-a1 is an orthosteric STING agonist that demonstrates an EC50 of 117 nM for the induction of IFNβ in human peripheral blood mononuclear cells (PBMCs). This compound is particularly relevant for research applications focused on monogenic autoinflammatory diseases, such as SAVI syndrome. Its ability to specifically activate the STING pathway makes diABZI-a1 a valuable tool for investigating immune responses and potential therapeutic interventions.
diABZI-a1 is an orthosteric STING agonist that demonstrates an EC50 of 117 nM for the induction of IFNβ in human peripheral blood mononuclear cells (PBMCs). This compound is particularly relevant for research applications focused on monogenic autoinflammatory diseases, such as SAVI syndrome. Its ability to specifically activate the STING pathway makes diABZI-a1 a valuable tool for investigating immune responses and potential therapeutic interventions.
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