Diaveridine

Catalog No.: A17000

DHFR inhibitor

Diaveridine

Diaveridine Chemical Structure

CAS NO. 5355-16-8

Diaveridine (EGIS-5645) is a dihydrofolate reductase (DHFR) inhibitor with a Ki of 11.5 nM for the wild type DHFR and also an antibacterial agent.

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500 mg
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1000 mg
$100.00
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Biological Activity

Diaveridine (EGIS-5645) is a dihydrofolate reductase (DHFR) inhibitor with a Ki of 11.5 nM for the wild type DHFR and also an antibacterial agent.
In vitro DMSO 22 mg/mL (84.52 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.42 mL 192.09 mL 384.19 mL
0.5 mM 7.68 mL 38.42 mL 76.84 mL
1 mM 3.84 mL 19.21 mL 38.42 mL
5 mM 0.77 mL 3.84 mL 7.68 mL

*The above data is based on the productmolecular weight 260.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17000
Actions Inhibitor
CAS No. 5355-16-8
Formula C13H16N4O2
M. Wt 260.29
Purity >98%
Synonyms EGIS-5645, EGIS5645, EGIS 5645
SMILES NC1=NC=C(CC2=CC=C(OC)C(OC)=C2)C(N)=N1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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