Diaveridine

Catalog No.: A17000

DHFR inhibitor

Diaveridine

Diaveridine Chemical Structure

CAS NO. 5355-16-8

Diaveridine (EGIS-5645) is a dihydrofolate reductase (DHFR) inhibitor with a Ki of 11.5 nM for the wild type DHFR and also an antibacterial agent.

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Biological Activity

Diaveridine (EGIS-5645) is a dihydrofolate reductase (DHFR) inhibitor with a Ki of 11.5 nM for the wild type DHFR and also an antibacterial agent.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.42 mL 192.09 mL 384.19 mL
0.5 mM 7.68 mL 38.42 mL 76.84 mL
1 mM 3.84 mL 19.21 mL 38.42 mL
5 mM 0.77 mL 3.84 mL 7.68 mL

*The above data is based on the productmolecular weight 260.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17000
Actions Inhibitor
M. Wt 260.29
Formula C13H16N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 5355-16-8
Synonyms EGIS-5645, EGIS5645, EGIS 5645
SMILES NC1=NC=C(CC2=CC=C(OC)C(OC)=C2)C(N)=N1

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