Diaveridine

Catalog No.: A17000
DHFR inhibitor
Diaveridine (EGIS-5645) is a dihydrofolate reductase (DHFR) inhibitor with a Ki of 11.5 nM for the wild type DHFR and also an antibacterial agent.
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Product Name Price Stock Qty
Diaveridine 500mg
$60.00
In stock
Diaveridine 1000mg
$100.00
In stock
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Biological Activity
Discription Diaveridine (EGIS-5645) is a dihydrofolate reductase (DHFR) inhibitor with a Ki of 11.5 nM for the wild type DHFR and also an antibacterial agent.
Product Information
Catalog Num A17000
Formula C13H16N4O2
Molecular Weight 260.29
CAS Number 5355-16-8
SMILES NC1=NC=C(CC2=CC=C(OC)C(OC)=C2)C(N)=N1
Synonyms EGIS-5645, EGIS5645, EGIS 5645
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 22 mg/mL (84.52 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 38.42 mL 192.09 mL 384.19 mL
0.5 mM 7.68 mL 38.42 mL 76.84 mL
1 mM 3.84 mL 19.21 mL 38.42 mL
5 mM 0.77 mL 3.84 mL 7.68 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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