Diazo Biotin-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide functional group that enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing entities. Its utility in linking biomolecules makes it a valuable tool in targeted protein degradation research and other applications involving the conjugation of proteins or small molecules.
Diazo Biotin-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an azide functional group that enables its participation in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing entities. Its utility in linking biomolecules makes it a valuable tool in targeted protein degradation research and other applications involving the conjugation of proteins or small molecules.
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