Diethylumbelliferyl phosphate (DEUP) acts as a selective and potent inhibitor of cholesterol esterase. This compound effectively disrupts steroidogenesis by inhibiting the transport of cholesterol into the mitochondria of steroidogenic cells, with an IC50 of 11.6 μM. DEUP is valuable in research applications focused on cholesterol metabolism and steroid hormone synthesis.
Diethylumbelliferyl phosphate (DEUP) acts as a selective and potent inhibitor of cholesterol esterase. This compound effectively disrupts steroidogenesis by inhibiting the transport of cholesterol into the mitochondria of steroidogenic cells, with an IC50 of 11.6 μM. DEUP is valuable in research applications focused on cholesterol metabolism and steroid hormone synthesis.
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