Dihydroartemisinin

Catalog No.: A10310

Dihydroartemisinin

Dihydroartemisinin Chemical Structure

CAS NO. 71939-50-9

Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself. It is a semi-synthetic derivative of artemisinin and is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs.

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Package Price Qty
100 mg
$70.00
200 mg
$90.00
500 mg
$130.00
10mM * 1mL in DMSO
$50.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Xinyu Zhou, .et al. Artemisinin Derivatives Stimulate DR5-Specific TRAIL-Induced Apoptosis by Regulating Wildtype P53, Cancers (Basel), 2020, Sep; 12(9): 2514 PMID: 32899699

Biological Activity

Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself. It is a semi-synthetic derivative of artemisinin and is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs.
Targets
In vitro DMSO Warmed: 52 mg/mL (182.87 mM)
Water Insoluble
Ethanol Warmed: 10 mg/mL (35.16 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.17 mL 175.84 mL 351.68 mL
0.5 mM 7.03 mL 35.17 mL 70.34 mL
1 mM 3.52 mL 17.58 mL 35.17 mL
5 mM 0.7 mL 3.52 mL 7.03 mL

*The above data is based on the productmolecular weight 284.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10310
CAS No. 71939-50-9
Formula C15H24O5
M. Wt 284.35
Purity >98%
Synonyms dihydroqinghaosu,artenimol, DHA
SMILES [H][[email protected]@]1(C([H])([H])C2([H])[H])[[email protected]]3([[email protected]@]([[email protected]@]4([H])C([H])([H])[H])([H])C([H])([H])C([H])([H])[[email protected]@]1([H])C([H])([H])[H])OO[[email protected]@]2(C([H])([H])[H])O[[email protected]@]3([H])O[[email protected]@]4([H])O[H]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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