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- Xinyu Zhou, .et al. Artemisinin Derivatives Stimulate DR5-Specific TRAIL-Induced Apoptosis by Regulating Wildtype P53, Cancers (Basel), 2020, Sep; 12(9): 2514 PMID: 32899699
Biological Activity
Dihydroartemisinin is the active metabolite of all artemisinin compounds (artemisinin, artesunate, artemether, etc.) and is also available as a drug in itself. It is a semi-synthetic derivative of artemisinin and is widely used as an intermediate in the preparation of other artemisinin-derived antimalarial drugs.
Targets
In vitro | DMSO | Warmed: 52 mg/mL (182.87 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 10 mg/mL (35.16 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 35.17 mL | 175.84 mL | 351.68 mL |
0.5 mM | 7.03 mL | 35.17 mL | 70.34 mL |
1 mM | 3.52 mL | 17.58 mL | 35.17 mL |
5 mM | 0.7 mL | 3.52 mL | 7.03 mL |
*The above data is based on the productmolecular weight 284.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10310 |
---|---|
CAS No. | 71939-50-9 |
Formula | C15H24O5 |
M. Wt | 284.35 |
Purity | >98% |
Synonyms | dihydroqinghaosu,artenimol, DHA |
SMILES | [H][C@@]1(C([H])([H])C2([H])[H])[C@]3([C@@]([C@@]4([H])C([H])([H])[H])([H])C([H])([H])C([H])([H])[C@@]1([H])C([H])([H])[H])OO[C@@]2(C([H])([H])[H])O[C@@]3([H])O[C@@]4([H])O[H] |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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