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Dinaciclib (SCH 727965)

Catalog No.: A11129
CDK Inhibitor
Adooq's Dinaciclib (SCH 727965) has been cited by 5 publications
Dinaciclib (SCH 727965) is a potent and selective cyclin-dependent kinase (CDK) inhibitor, selectively inhibiting CDK1, CDK2, CDK5 and CDK9 with IC50 values of 3, 1, 1 and 4 nM respectively.
Dinaciclib (SCH 727965)
Grouped product items
Size Price Stock Qty
2mg
$40.00
In stock
5mg
$65.00
In stock
10mg
$115.00
In stock
25mg
$235.00
In stock
50mg
$375.00
In stock
100mg
$685.00
In stock
10mM * 1mL in DMSO
$70.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Dinaciclib (SCH 727965) has been cited by 5 publications
  • Vineeta Teotia, .et al. , ACS Omega, 2024, Sep 13;9(38):39873-39892 PMID: 39346877
  • Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138
  • Sepideh Izadi, .et al. , Pharm Res, 2020, Sep 17;37(10):196 PMID: 32944844
  • Shahin Hallaj, .et al. , Life Sci, 2020, Jul 26 PMID: 32726663
  • Washio I, .et al. , Drug Metab Dispos, 2018, Mar;46(3):214-222 PMID: 29246888
    • Biological Activity
    Discription Dinaciclib (SCH 727965) is a potent and selective cyclin-dependent kinase (CDK) inhibitor, selectively inhibiting CDK1, CDK2, CDK5 and CDK9 with IC50 values of 3, 1, 1 and 4 nM respectively.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A11129
    Formula C21H28N6O2
    Molecular Weight 396.5
    CAS Number 779353-01-4
    SMILES CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCC[C@H]4CCO
    Synonyms SCH727965, SCH-727965
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO Warmed: 22 mg/mL (55.48 mM)
    Water Insoluble
    Ethanol Warmed: 7 mg/mL (17.65 mM)
    In vivo 2% DMSO+30% PEG 300+ddH2O 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.22 mL 126.1 mL 252.21 mL
    0.5 mM 5.04 mL 25.22 mL 50.44 mL
    1 mM 2.52 mL 12.61 mL 25.22 mL
    5 mM 0.5 mL 2.52 mL 5.04 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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    Cell Cycle > CDK
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