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Dioscin (Collettiside III)


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Catalog No. A10314

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Dioscin 5mg A10314-5

Regular Price: $90.00

Special Price: $81.00

Dioscin 10mg A10314-10

Regular Price: $160.00

Special Price: $144.00

Dioscin 50mg A10314-50

Regular Price: $450.00

Special Price: $405.00

Dioscin 100mg A10314-100

Regular Price: $750.00

Special Price: $675.00

Dioscin (Collettiside III) 10mM * 1mL in DMSO A10314-10mM-D

Regular Price: $215.00

Special Price: $193.50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Dioscin (Collettiside III) is extracted and isolated from Polygonatum Zanlanscianense Pamp with IC50 of 2.6, 0.8, 7.5, and 4.5 μM for the inhibition of the growth of the MDA-MB-435, H14, HL60, and HeLa cell lines, respectively.

Dioscin (Collettiside III)

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Chemical Information

Catalog Num A10314
Actions N/A
M. Wt 869
Formula C45H72O16
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 19057-60-4
Synonyms Collettiside III, CCRIS 4123
SMILES code C[[email protected]@H]1CC[[email protected]@]2([[email protected]]([[email protected]]3[[email protected]@H](O2)C[[email protected]@H]4[[email protected]@]3(CC[[email protected]]5[[email protected]]4CC=C6[[email protected]@]5(CC[[email protected]@H](C6)O[[email protected]]7[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O7)CO)O[[email protected]]8[[email protected]@H]([[email protected]@H]([[email protected]]([[email protected]@H](O8)C)O)O)O)O)O[[email protected]]9[[email protected]@H]([[email protected]@H]([[email protected]]([[email protected]@H](O9)C)O)O)O)C)C)C)OC1
Chemical Name Diosgenin bis-alpha-L-rhamnopyranosyl)-(1-2 and 1-4)-beta-D-glucopyranoside

Biological Activity

Dioscin (Collettiside III) is extracted and isolated from Polygonatum Zanlanscianense Pamp with IC50 of 2.6, 0.8, 7.5, and 4.5 μM for the inhibition of the growth of the MDA-MB-435, H14, HL60, and HeLa cell lines, respectively.


Solubility (25°C)* In vitro DMSO 174 mg/mL (200.22 mM)
Water <1 mg/mL (<1 mM)
Ethanol 22 mg/mL (25.31 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.51 mL 57.54 mL 115.07mL
0.5 mM 2.3 mL 11.51 mL 23.01 mL
1 mM 1.15 mL 5.75 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL

*The above data is based on the productmolecular weight 869. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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