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Biological Activity
Dioscin (Collettiside III) is extracted and isolated from Polygonatum Zanlanscianense Pamp with IC50 of 2.6, 0.8, 7.5, and 4.5 μM for the inhibition of the growth of the MDA-MB-435, H14, HL60, and HeLa cell lines, respectively.
| In vitro | DMSO | 86 mg/mL (98.95 mM) | |
| Water | Insoluble | ||
| Ethanol | 19 mg/mL (21.86 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.51 mL | 57.54 mL | 115.07 mL |
| 0.5 mM | 2.3 mL | 11.51 mL | 23.01 mL |
| 1 mM | 1.15 mL | 5.75 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
*The above data is based on the productmolecular weight 869. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10314 |
|---|---|
| CAS No. | 19057-60-4 |
| Formula | C45H72O16 |
| M. Wt | 869 |
| Purity | >98% |
| Synonyms | Collettiside III, CCRIS 4123 |
| SMILES | C[[email protected]@H]1CC[[email protected]@]2([[email protected]]([[email protected]]3[[email protected]@H](O2)C[[email protected]@H]4[[email protected]@]3(CC[[email protected]]5[[email protected]]4CC=C6[[email protected]@]5(CC[[email protected]@H](C6)O[[email protected]]7[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O7)CO)O[[email protected]]8[[email protected]@H]([[email protected]@H]([[email protected]]([[email protected]@H](O8)C)O)O)O)O)O[[email protected]]9[[email protected]@H]([[email protected]@H]([[email protected]]([[email protected]@H](O9)C)O)O)O)C)C)C)OC1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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