DJ4

Name: DJ4
Brand: Adooq Bioscience
SKU: A24494
Rating: 5 (288 reviews)

Catalog No.: A24494

ROCK1/2 inhibitor

DJ4 is an ATP-competitive inhibitor of ROCK1/2 and MRCKα/β, with IC₅₀ values of 5 nM and 50 nM for ROCK1 and ROCK2, and 10 nM and 100 nM for MRCKα and MRCKβ, respectively. It blocks stress fiber formation and induces apoptosis, making it a valuable compound for cancer research.

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Grouped product items
Size	Price	Stock
5mg	$126.00	In stock
10mg	$217.00	In stock
50mg	$644.00	In stock
100mg	$1,260.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	DJ4 is an ATP-competitive inhibitor of ROCK1/2 and MRCKα/β, with IC₅₀ values of 5 nM and 50 nM for ROCK1 and ROCK2, and 10 nM and 100 nM for MRCKα and MRCKβ, respectively. It blocks stress fiber formation and induces apoptosis, making it a valuable compound for cancer research.

Product Information

Catalog Num	A24494
Formula	C19H16N4OS
Molecular Weight	348.42
CAS Number	1681020-24-5
SMILES	O=C1N/C(S/C1=C/C2=CNC3=C2C=CC=N3)=N\CCC4=CC=CC=C4
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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