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Biological Activity
DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 12.75 mL | 63.74 mL | 127.49 mL |
0.5 mM | 2.55 mL | 12.75 mL | 25.5 mL |
1 mM | 1.27 mL | 6.37 mL | 12.75 mL |
5 mM | 0.25 mL | 1.27 mL | 2.55 mL |
*The above data is based on the productmolecular weight 784.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15960 |
---|---|
Actions | Inhibitor |
CAS No. | 138148-68-2 |
Formula | C36H50ClN3O10S2 |
M. Wt | 784.38 |
Purity | >98% |
Synonyms | DM1-SSMe |
SMILES | C[[email protected]@H]1[[email protected]@H]2C[[email protected]](NC(O2)=O)(O)[[email protected]](OC)/C=C\C=C(C)\CC3=CC(N(C)C(C[[email protected]@H](OC([[email protected]@H](N(C(CCSSC)=O)C)C)=O)[[email protected]@]4(C)C1O4)=O)=C(Cl)C(OC)=C3 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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