DM1-Sme

Catalog No.: A15960

maytansinoid microtubular inhibitor

DM1-Sme

DM1-Sme Chemical Structure

CAS NO. 138148-68-2

DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group.

Availability: In stock

Package Price Qty
5 mg
$320.00
10 mg
$480.00
50 mg
$1,400.00
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Biological Activity

DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.75 mL 63.74 mL 127.49 mL
0.5 mM 2.55 mL 12.75 mL 25.5 mL
1 mM 1.27 mL 6.37 mL 12.75 mL
5 mM 0.25 mL 1.27 mL 2.55 mL

*The above data is based on the productmolecular weight 784.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15960
Actions Inhibitor
CAS No. 138148-68-2
Formula C36H50ClN3O10S2
M. Wt 784.38
Purity >98%
Synonyms DM1-SSMe
SMILES C[[email protected]@H]1[[email protected]@H]2C[[email protected]](NC(O2)=O)(O)[[email protected]](OC)/C=C\C=C(C)\CC3=CC(N(C)C(C[[email protected]@H](OC([[email protected]@H](N(C(CCSSC)=O)C)C)=O)[[email protected]@]4(C)C1O4)=O)=C(Cl)C(OC)=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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