DM1-Sme

Catalog No.: A15960

maytansinoid microtubular inhibitor

DM1-Sme

DM1-Sme Chemical Structure

CAS NO. 138148-68-2

DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group.

Availability: In stock

Package Price Qty
5 mg
$320.00
10 mg
$480.00
50 mg
$1,400.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.75 mL 63.74 mL 127.49 mL
0.5 mM 2.55 mL 12.75 mL 25.5 mL
1 mM 1.27 mL 6.37 mL 12.75 mL
5 mM 0.25 mL 1.27 mL 2.55 mL

*The above data is based on the productmolecular weight 784.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15960
Actions Inhibitor
M. Wt 784.38
Formula C36H50ClN3O10S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 138148-68-2
Synonyms DM1-SSMe
SMILES C[[email protected]@H]1[[email protected]@H]2C[[email protected]](NC(O2)=O)(O)[[email protected]](OC)/C=C\C=C(C)\CC3=CC(N(C)C(C[[email protected]@H](OC([[email protected]@H](N(C(CCSSC)=O)C)C)=O)[[email protected]@]4(C)C1O4)=O)=C(Cl)C(OC)=C3

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