DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite functions as a phosphoramidite derivative of 5-fluoro-2'-deoxycytidine, specifically designed for use in solid-phase oligonucleotide synthesis. This reagent enables the incorporation of the nucleoside analogue into DNA sequences, facilitating studies of nucleotide metabolism, DNA repair mechanisms, and the effects of fluorinated nucleotides on enzyme activity. Its chemical structure allows for efficient coupling and enhances the stability of synthesized oligonucleotides, contributing to a range of molecular biology applications.
DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite functions as a phosphoramidite derivative of 5-fluoro-2'-deoxycytidine, specifically designed for use in solid-phase oligonucleotide synthesis. This reagent enables the incorporation of the nucleoside analogue into DNA sequences, facilitating studies of nucleotide metabolism, DNA repair mechanisms, and the effects of fluorinated nucleotides on enzyme activity. Its chemical structure allows for efficient coupling and enhances the stability of synthesized oligonucleotides, contributing to a range of molecular biology applications.
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