DN-108 is a thiazolidinedione derivative that serves as an orally active agonist for peroxisome proliferator-activated receptor γ (PPARγ). This compound exhibits notable antidiabetic properties, effectively improving hyperglycemia, hypertriglyceridemia, and hyperinsulinemia in diabetic mouse models. DN-108 enhances glucose uptake in tissues, such as increasing 2-deoxyglucose uptake in L6 muscle cells, and inhibits fatty acid synthase activity. This makes DN-108 a valuable tool for research focused on type 2 diabetes.
DN-108 is a thiazolidinedione derivative that serves as an orally active agonist for peroxisome proliferator-activated receptor γ (PPARγ). This compound exhibits notable antidiabetic properties, effectively improving hyperglycemia, hypertriglyceridemia, and hyperinsulinemia in diabetic mouse models. DN-108 enhances glucose uptake in tissues, such as increasing 2-deoxyglucose uptake in L6 muscle cells, and inhibits fatty acid synthase activity. This makes DN-108 a valuable tool for research focused on type 2 diabetes.
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