Nucleoside Antimetabolite/Analog

Items 601-650 of 1704

Page
per page
Set Descending Direction
Catalog No.
Product Name
Application
Product Information
Citations
  1. Nucleoside Metabolite

    (R)-2-Hydroxy-α-linolenic acid is a nucleoside metabolite that plays a crucial role in lipid metabolism. This compound is known to exhibit various biological activities, including anti-inflammatory effects and modulation of cellular signaling pathways. It is utilized in research applications related to lipid biochemistry and metabolic disorders, aiding in the understanding of physiological processes and potential therapeutic targets.
  2. Purine Nucleoside Analog

    3’-Deoxy-N6-ethyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic development. Additionally, this compound can be employed in various studies related to nucleoside metabolism and its effects on cell proliferation.
  3. Antiviral Agent

    Detiviciclovir is an antiviral nucleoside analogue that targets viral DNA synthesis. It exhibits potent activity against a range of viral infections by inhibiting the replication of viral genomes. This compound is useful in research applications focused on developing antiviral therapies and understanding viral replication mechanisms.
  4. Nucleoside Metabolite

    Acetyl adenylate (5'-Acetylphosphoadenosine) is a nucleoside metabolite that primarily functions as an intermediate in nucleotide metabolism. This compound plays a crucial role in cellular energy transfer and regulation of various biochemical pathways. Acetyl adenylate is often utilized in research applications involving nucleotide signaling and enzymatic assays, providing insights into metabolic processes and cellular functions.
  5. Nucleoside Metabolite

    2-Formylaminobenzaldehyde is a nucleoside metabolite that plays a significant role in biochemical processes. It exhibits key biological activities that are vital for studying nucleoside metabolism and related pathways. This compound is commonly utilized in research applications focused on enzymatic reactions and metabolic profiling in biological systems.
  6. Purine Nucleoside Analog

    2′-Deoxy-5-methylisocytidine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in indolent lymphoid malignancies. Its mode of action includes the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This reagent can be utilized in studies aimed at understanding tumor biology and developing novel therapeutic strategies.
  7. Nucleoside Metabolite

    5'-Butyrylphosphoinosine is a nucleoside metabolite that plays a critical role in cellular signaling pathways. This compound acts as a key regulator in the synthesis and metabolism of inositol phosphate, impacting various biological processes including cell proliferation and differentiation. It is primarily used in biochemical and pharmacological research applications to study metabolic pathways and signal transduction mechanisms.
  8. Purine Nucleoside Analog

    2'-Deoxy-2'-fluoro-N3-[(pyrid-2-yl)methyl]-beta-D-arabinouridine is a purine nucleoside analog that interferes with DNA synthesis, leading to antitumor effects. This compound exhibits significant biological activity against indolent lymphoid malignancies, promoting apoptosis in affected cells. It serves as a valuable tool for cancer research, particularly in the exploration of new therapeutic strategies targeting lymphoid tumors.
  9. Purine Nucleoside Analog

    3-Deaza-4’-C-methyluridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the promotion of apoptosis in cancer cells. This compound is invaluable for research applications focused on cancer biology and therapeutic development.
  10. Uridine Analog

    3’-beta-C-Methyluridine is an uridine analog that serves as a valuable tool for studying its pharmacological potential in epilepsy. This compound may exhibit antiepileptic properties and can be utilized in research focused on anticonvulsant and anxiolytic activities. Additionally, it holds promise for the development of novel antihypertensive agents, making it relevant for various therapeutic applications.
  11. Purine Nucleoside Analog

    Rev 2’-O-MOE-G(iBu)-5’-amidite is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable in research applications aimed at understanding cancer biology and developing novel therapeutic strategies.
  12. Click Chemistry Reagent

    Pyrene phosphoramidite dU is a versatile click chemistry reagent that incorporates pyrene moieties into nucleic acids. This compound exhibits strong blue fluorescence upon incorporation into DNA, making it an effective tool for studying nucleic acid interactions and dynamics. Pyrene phosphoramidite dU is widely used in applications such as DNA labeling, imaging, and the development of fluorescent probes for biophysical studies.
  13. Purine Nucleoside Analog

    3'-Amino-3'-deoxycytidine is a purine nucleoside analog that primarily targets DNA synthesis inhibition. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as apoptosis induction and interruption of cellular replication processes. It is a valuable reagent for research applications focused on cancer biology and therapeutic development.
  14. Cytidine Analog

    5-(2-Hydroxyethyl)cytidine is a cytidine analog known for its ability to inhibit DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research and epigenetic studies. Its unique mechanism allows for the exploration of methylation patterns and their impact on gene expression in various biological contexts.
  15. Purine Nucleoside Analog

    2-Chloro-N6,N6-dimethyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This reagent is valuable for research applications focused on cancer biology and therapeutic development.
  16. Nucleoside Metabolite

    L-4-Hydroxyglutamate semialdehyde is a derivative of L-glutamic 5-semialdehyde, featuring a hydroxyl group at the 4-position. This compound acts as a vital nucleoside metabolite in various biological systems, including yeast, mice, and humans. Its biological activity is closely linked to the metabolic pathways of arginine and proline, making it relevant for research into amino acid metabolism and related physiological processes.
  17. Nucleoside Metabolite

    5-Ureidoimidazole-4-carboxylic acid is a nucleoside metabolite that serves as a key intermediate in purine metabolism. This compound has been utilized in research to study its role in nucleotide synthesis and its potential implications in metabolic disorders. Its biological activity can provide insights into cellular processes and contribute to investigations of metabolic pathways.
  18. Purine Nucleoside Analog

    2',3'-Dideoxy-3'-fluorouridine is a purine nucleoside analog that primarily inhibits DNA synthesis. Its key biological activity includes inducing apoptosis, which contributes to its broad antitumor efficacy against indolent lymphoid malignancies. This compound is valuable for research applications targeting cancer therapeutics and exploring mechanisms of nucleoside metabolism in tumor cells.
  19. Nucleoside Metabolite

    N,N-Dihydroxy-L-tyrosine is a nucleoside metabolite that acts as a precursor in biochemical pathways. This compound is involved in the regulation of neurotransmitter synthesis and may influence metabolic processes related to phenolic compounds. Its biological activity makes it valuable for research in neurobiology and metabolic studies.
  20. Purine Nucleoside Analog

    5-Methylcyclocytidine hydrochloride is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is suitable for investigating cellular proliferation and apoptosis pathways in various cancer models.
  21. Purine Nucleoside Analog

    4'-α-C-Methylcytidine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, which can lead to the induction of apoptosis in cancer cells. This compound is an important tool in cancer research, providing insights into therapeutic strategies and the molecular pathways underlying tumor progression.
  22. Nucleoside Metabolite

    2-Oxo-3-sulfinopropanoic acid, also known as β-Sulfinyl pyruvate, is a nucleoside metabolite resulting from the deamination of cysteine sulfinic acid. It is known to decomposed into pyruvate and sulfite, thus playing a significant role in metabolic pathways. This compound is valuable for researchers investigating sulfur amino acid metabolism and related biochemical processes.
  23. Cytidine Analog

    5-Fluoro-4’-C-methylcytidine is a cytidine nucleoside analog that functions as an inhibitor of DNA methyltransferases. This compound exhibits potential anti-metabolic and anti-tumor activities, making it a valuable tool in cancer research. Its ability to interfere with DNA methylation processes facilitates studies on epigenetic regulation and therapeutic strategies targeting methylation pathways.
  24. Purine Nucleoside Analog

    7-Cyano-7-deazaguanosine is a purine nucleoside analog that exhibits significant antitumor activity. This compound targets indolent lymphoid malignancies through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. Its application in cancer research facilitates the exploration of therapeutic strategies against various malignant cell types.
  25. Purine Nucleoside Analog

    2’-Beta-C-Ethynyl inosine is a purine nucleoside analog that exhibits significant anticancer activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, 2’-Beta-C-Ethynyl inosine serves as a click chemistry reagent due to its alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating various bioconjugation applications.
  26. 5'-AMP Analogue

    5'-AMPS is an analogue of 5'-AMP that functions as a substrate and competitive inhibitor of enzymes that interact with 5'-AMP. This compound is utilized in research to explore the regulatory mechanisms of cellular signaling pathways involving AMP, as well as to study enzyme kinetics. Its unique properties make it a valuable tool for dissecting the roles of AMP-related metabolic processes in various biological systems.
  27. Uridine Analog

    3′,5′-Bis-O-(triphenylmethyl)uridine is a uridine analog targeting nucleotide metabolism. This compound demonstrates potential antiepileptic properties and is utilized in research to explore anticonvulsant and anxiolytic activities. Additionally, it serves as a valuable tool in the development of novel antihypertensive agents, making it relevant for various therapeutic studies.
  28. Purine Nucleoside Analog

    5′-Azido-2′,5′-dideoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity by targeting indolent lymphoid malignancies. Its primary mechanisms include inhibition of DNA synthesis and induction of apoptosis. This compound is also a valuable click chemistry reagent, featuring an azide group that allows for copper-catalyzed azide-alkyne cycloaddition reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules featuring DBCO or BCN groups, making it suitable for various biochemical applications.
  29. Uridine Analog

    2’,3’-Di-O-isopropylidene-4’-alpha-C-azidouridine is a uridine analog that serves as a valuable tool in the study of anticonvulsant and anxiolytic properties, with potential applications in developing antihypertensive agents. This compound features an azide group, enabling it to function as a click chemistry reagent through copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN functionalized compounds, facilitating bioconjugation and tracer development in chemical biology.
  30. Adenosine Analog

    N6-Benzyl-2’-C-methyladenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits vasodilatory effects in smooth muscle and demonstrates potential in inhibiting cancer progression. It serves as a valuable tool in studies focusing on cardiovascular function and cancer biology, facilitating research into therapeutic strategies for related conditions.
  31. Purine Nucleoside Analog

    2'-Deoxy-2'-fluoro-3',5'-bis-O-TBDMS-uridine is a purine nucleoside analog with significant antitumor activity. It primarily targets indolent lymphoid malignancies by inhibiting DNA synthesis and inducing apoptosis. This compound serves as a valuable reagent for research applications focused on cancer biology and therapeutic development.
  32. Purine Nucleoside Analog

    2',3'-Didehydro-2',3'-dideoxyuridine is a purine nucleoside analog that exhibits significant antitumor properties, particularly in the treatment of indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for research applications focused on cancer biology and therapeutic development.
  33. Purine Nucleoside Analog

    N6-Dimethyldeoxyadenosine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis and the induction of apoptotic pathways in cancer cells. This compound serves as a valuable tool in cancer research, contributing to the development of therapeutic strategies targeting malignant lymphoid tissues.
  34. Product of Ergothionase

    Thiourocanic acid is a metabolite resulting from the enzymatic activity of ergothionase on the substrate ergothioneine. This compound has been studied for its potential biological activities, including antioxidant properties. It serves as a useful tool in research exploring the metabolic pathways of thiol compounds and their roles in cellular protection and oxidative stress responses.
  35. Purine Nucleoside Analog

    3,5-Di-O-benzoyl-2-deoxy-2-fluoro-5-trifluoromethyl-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research, particularly for targeting indolent lymphoid malignancies. This compound is suitable for studies focused on cancer treatment and the development of novel therapeutic strategies.
  36. Purine Nucleoside Analog

    N1-Methyl ara-uridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound can be utilized to explore therapeutic approaches in various malignancies and enhance understanding of nucleoside analog efficacy.
  37. Purine Nucleoside Analog

    3’-Deoxy-3’-fluoro-xyloadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly in the treatment of indolent lymphoid malignancies. This compound acts through mechanisms such as the inhibition of DNA synthesis and the induction of apoptosis. Its applications in cancer research make it a valuable tool for exploring therapeutic strategies against various hematological cancers.
  38. Nucleoside Analogue

    Methyl 2-deoxy-3,5-di-O-benzoyl-2-fluoro-4-thio-beta-D-arabinopentofuranoside is a nucleoside analogue targeting viral nucleic acid synthesis. This compound exhibits potential antiviral activity and is utilized in research related to viral infections and nucleoside-related pathways. Its structural modifications make it a valuable tool in exploring the mechanisms of nucleic acid function and inhibition in biological systems.
  39. Purine Nucleoside Analog

    2-Amino-1-β-D-arabinofuranosyl-5-methyl-4(1H)-pyrimidinone is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, which contributes to the induction of apoptosis in cancer cells. This compound is valuable for research applications centered on cancer biology and therapeutic development.
  40. Purine Nucleoside Analog

    2’,3’,5’-Tri-O-benzyl-4’-thio-arabinouridine is a purine nucleoside analog that demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound serves as a valuable tool for research applications focused on cancer biology and the development of therapeutic strategies for lymphoid cancers.
  41. Purine Nucleoside Analog

    5’-O-(p-Toluoyl)-2’-O-acetyl-3’-deoxy-3’-fluoro-6-chloroinosine is a purine nucleoside analog that exhibits significant antitumor activity, targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This reagent is useful in cancer research, particularly in studies aimed at understanding the efficacy of nucleotide analogs in therapeutic applications.
  42. Purine Nucleoside Analog

    6-Aza-2'-deoxyuridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism involves the inhibition of DNA synthesis, leading to the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic development targeting nucleotide metabolism pathways.
  43. Radiosensitizer

    RA-263 is a 2-nitroimidazole nucleoside that functions as a radiosensitizer. This compound enhances the efficacy of radiation therapy by increasing the sensitivity of tumor cells to ionizing radiation. RA-263 is primarily utilized in cancer research to investigate combined modality treatments and to explore mechanisms of radioresistance in various tumor models.
  44. Purine Nucleoside Analog

    2-Amino-6-chloropurine-9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside is a purine nucleoside analog that exerts its primary effects by inhibiting DNA synthesis. This compound demonstrates significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action includes the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development.
  45. Purine Nucleoside Analog

    2’-β-C-Methyl-2-thiouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is utilized to explore therapeutic strategies for various malignancies and to study the role of nucleoside analogs in cancer treatment.
  46. Guanosine Analog

    N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is a guanosine analog that acts primarily through the activation of Toll-like receptor 7 (TLR7). This compound exhibits immunostimulatory properties and has been demonstrated to induce type I interferons in various animal models, leading to antiviral effects. It is a valuable tool for research in virology and immunology, facilitating investigations into host responses to viral infections and the modulation of immune pathways.
  47. Cytidine Analog

    N4-Benzoyl-5'-O-DMT-5-methylcytidine is a cytidine analog that primarily targets DNA methyltransferases, thereby inhibiting their activity. This compound exhibits potential anti-metabolic and anti-tumor properties, making it valuable in cancer research and studies focused on epigenetic regulation. Its ability to modulate DNA methylation provides avenues for investigating therapeutic strategies against malignancies.
  48. Purine Nucleoside Analog

    4′,5′-Didehydro-5′-deoxy-5-methyluridine is a purine nucleoside analog with significant antitumor properties. This compound exhibits its anticancer effects primarily through the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in the study of indolent lymphoid malignancies. Its use in research can facilitate the understanding of nucleoside metabolism and the development of therapeutic strategies in cancer treatment.
  49. Nucleoside Metabolite

    Bis(glutathionyl)spermine disulfide is a nucleoside metabolite that plays a crucial role in cellular redox balance. This compound is known for its ability to regulate cellular antioxidant systems and modulate intracellular signaling pathways. It is primarily used in research applications focusing on oxidative stress, cell proliferation, and apoptosis mechanisms.
  50. Purine Nucleoside Analog

    3’-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)-L-arabinofuranose is a purine nucleoside analog that inhibits DNA synthesis and induces apoptosis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. It serves as a valuable tool in cancer research and therapeutic development.

Items 601-650 of 1704

Page
per page
Set Descending Direction