2’-Beta-C-Ethynyl inosine is a purine nucleoside analog that exhibits significant anticancer activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, 2’-Beta-C-Ethynyl inosine serves as a click chemistry reagent due to its alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating various bioconjugation applications.
2’-Beta-C-Ethynyl inosine is a purine nucleoside analog that exhibits significant anticancer activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. Additionally, 2’-Beta-C-Ethynyl inosine serves as a click chemistry reagent due to its alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, facilitating various bioconjugation applications.
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