DNP-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs, targeting targeted protein degradation pathways. This compound features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing molecules, as well as with those bearing DBCO or BCN groups. Its utility in click chemistry enables precise conjugation strategies essential for advancing research in therapeutic protein modulation.
DNP-PEG3-azide is a PEG-based linker designed for use in the synthesis of PROTACs, targeting targeted protein degradation pathways. This compound features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) with alkyne-containing molecules, as well as with those bearing DBCO or BCN groups. Its utility in click chemistry enables precise conjugation strategies essential for advancing research in therapeutic protein modulation.
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