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$0.00 - Ogawa C, .et al. Comparison of Chemical Behavior of Original and Generic Docetaxel Formulations as Non-alcoholic Preparations: Discussion about Diluent Solvents for Docetaxel, Yakugaku Zasshi, 2018, 138(7):973-984 PMID: 29962477
Biological Activity
Docetaxel trihydrate, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules.
| In vitro | DMSO | 98 mg/mL (113.69 mM) | |
| Water | Insoluble | ||
| Ethanol | 98 mg/mL (113.69 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.6 mL | 58.01 mL | 116.02 mL |
| 0.5 mM | 2.32 mL | 11.6 mL | 23.2 mL |
| 1 mM | 1.16 mL | 5.8 mL | 11.6 mL |
| 5 mM | 0.23 mL | 1.16 mL | 2.32 mL |
*The above data is based on the productmolecular weight 861.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15070 |
|---|---|
| CAS No. | 148408-66-6 |
| Formula | C43H59NO17 |
| M. Wt | 861.93 |
| Purity | >98% |
| Synonyms | Taxotere Trihydrate |
| SMILES | CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O.O.O.O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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