Docetaxel Trihydrate

Catalog No.: A15070

Docetaxel Trihydrate

Docetaxel Trihydrate Chemical Structure

CAS NO. 148408-66-6

Docetaxel trihydrate, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules.

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500 mg
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  • Ogawa C, .et al. Comparison of Chemical Behavior of Original and Generic Docetaxel Formulations as Non-alcoholic Preparations: Discussion about Diluent Solvents for Docetaxel, Yakugaku Zasshi, 2018, 138(7):973-984 PMID: 29962477

Biological Activity

Docetaxel trihydrate, an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules.
In vitro DMSO 98 mg/mL (113.69 mM)
Water Insoluble
Ethanol 98 mg/mL (113.69 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.6 mL 58.01 mL 116.02 mL
0.5 mM 2.32 mL 11.6 mL 23.2 mL
1 mM 1.16 mL 5.8 mL 11.6 mL
5 mM 0.23 mL 1.16 mL 2.32 mL

*The above data is based on the productmolecular weight 861.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15070
CAS No. 148408-66-6
Formula C43H59NO17
M. Wt 861.93
Solubility DMSO
Purity >98%
Synonyms Taxotere Trihydrate
SMILES CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O.O.O.O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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