Doramapimod hydrochloride

Catalog No.: A39425
p38 MAPK Inhibitor
Doramapimod hydrochloride is a selective inhibitor of p38 MAPK, a key regulator in inflammatory responses. This compound effectively attenuates the production of pro-inflammatory cytokines, including TNF-α and IL-1β, in response to LPS, LTA, and PGN stimulation. Its potent anti-inflammatory properties make Doramapimod hydrochloride valuable for researching various autoimmune diseases and inflammatory pathways.
Grouped product items
Size Price Stock Qty
5mg
$40.00
In stock
10mg
$65.00
In stock
25mg
$125.00
In stock
50mg
$205.00
In stock
100mg
$320.00
In stock
500mg
$1,090.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDoramapimod hydrochloride is a selective inhibitor of p38 MAPK, a key regulator in inflammatory responses. This compound effectively attenuates the production of pro-inflammatory cytokines, including TNF-α and IL-1β, in response to LPS, LTA, and PGN stimulation. Its potent anti-inflammatory properties make Doramapimod hydrochloride valuable for researching various autoimmune diseases and inflammatory pathways.
Product Information
Catalog NumA39425
FormulaC31H38ClN5O3
Molecular Weight564.12
CAS Number1283526-53-3
SMILESO=C(NC1=CC(C(C)(C)C)=NN1C2=CC=C(C)C=C2)NC3=C4C=CC=CC4=C(OCCN5CCOCC5)C=C3.Cl
SynonymsBIRB 796 hydrochloride
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