Doxorubicin

Catalog No.: A14403

Topoisomerase II inhibitor

Doxorubicin

Doxorubicin Chemical Structure

CAS NO. 23214-92-8

Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.

Availability: In stock

Package Price Qty
50 mg
$45.00
100 mg
$75.00
500 mg
$250.00
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  • Abdelrehim A, .et al. The use of tail-anchored protein chimeras to enhance liposomal cargo delivery, PLoS One, 2019, Feb 22;14(2):e0212701 PMID: 30794671
  • J Wei, .et al. Profiling the surface proteome identifies actionable biology for TSC1 mutant cells beyond mTORC1 signaling, bioRxiv, 2018, 2018

Biological Activity

Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 91.99 mL 183.99 mL
0.5 mM 3.68 mL 18.4 mL 36.8 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14403
Actions Inhibitor
M. Wt 543.52
Formula C27H29NO11
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 23214-92-8
Synonyms Adriamycin, Hydroxydaunorubicin
SMILES C[[email protected]]1[[email protected]]([[email protected]](C[[email protected]@H](O1)O[[email protected]]2C[[email protected]@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O

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