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Topoisomerase II inhibitor

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Catalog No. A14403

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Doxorubicin 50mg A14403-50
Doxorubicin 100mg A14403-100
Doxorubicin 500mg A14403-500

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.


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Publications citing Adooq Products
Doxorubicin Citations (2)
  • Abdelrehim A, .et al. The use of tail-anchored protein chimeras to enhance liposomal cargo delivery, PLoS One, 2019, Feb 22;14(2):e0212701 PMID: 30794671
  • J Wei, .et al. Profiling the surface proteome identifies actionable biology for TSC1 mutant cells beyond mTORC1 signaling, bioRxiv, 2018, 2018

Chemical Information

Catalog Num A14403
Actions Inhibitor
M. Wt 543.52
Formula C27H29NO11
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 23214-92-8
Synonyms Adriamycin, Hydroxydaunorubicin
SMILES C[[email protected]]1[[email protected]]([[email protected]](C[[email protected]@H](O1)O[[email protected]]2C[[email protected]@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O

Biological Activity

Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 91.99 mL 183.99mL
0.5 mM 3.68 mL 18.4 mL 36.8 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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