(E)-tert-Butyldimethyl((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-1-yl)oxy)silane serves as a versatile PROTAC linker, facilitating the assembly of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins via the ubiquitin-proteasome system and is instrumental in drug discovery and development. Its unique structure allows for effective conjugation, enhancing cellular permeability and targeting specificity in therapeutic applications.
(E)-tert-Butyldimethyl((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-3-en-1-yl)oxy)silane serves as a versatile PROTAC linker, facilitating the assembly of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins via the ubiquitin-proteasome system and is instrumental in drug discovery and development. Its unique structure allows for effective conjugation, enhancing cellular permeability and targeting specificity in therapeutic applications.
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