(E/Z)-Elafibranor (also known as (E/Z)-GFT505) is a dual agonist of the peroxisome proliferator-activated receptors alpha (PPARα) and delta (PPARδ), exhibiting EC50 values of 45 nM and 175 nM, respectively. This compound plays a significant role in lipid metabolism and inflammation modulation, making it valuable for research in metabolic disorders, obesity, and non-alcoholic fatty liver disease (NAFLD). Its ability to simultaneously target multiple pathways positions (E/Z)-Elafibranor as a promising candidate for therapeutic interventions in metabolic diseases.
(E/Z)-Elafibranor (also known as (E/Z)-GFT505) is a dual agonist of the peroxisome proliferator-activated receptors alpha (PPARα) and delta (PPARδ), exhibiting EC50 values of 45 nM and 175 nM, respectively. This compound plays a significant role in lipid metabolism and inflammation modulation, making it valuable for research in metabolic disorders, obesity, and non-alcoholic fatty liver disease (NAFLD). Its ability to simultaneously target multiple pathways positions (E/Z)-Elafibranor as a promising candidate for therapeutic interventions in metabolic diseases.
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