E3 Ligase Ligand-linker Conjugate 115

Catalog No.: A80222
E3 Ligase Ligand-Linker Conjugate
E3 Ligase Ligand-linker Conjugate 115 is a potent E3 ubiquitin ligase ligand combined with a linker, designed for the development of targeted protein degradation strategies. This compound serves as a crucial component in synthesizing PROTAC SMARCA2/4-degrader-27, enabling researchers to investigate the modulation of specific protein levels through ubiquitin-proteasome pathway engagement. Its application in chemical biology provides a valuable tool for studying protein function and regulation in various cellular contexts.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionE3 Ligase Ligand-linker Conjugate 115 is a potent E3 ubiquitin ligase ligand combined with a linker, designed for the development of targeted protein degradation strategies. This compound serves as a crucial component in synthesizing PROTAC SMARCA2/4-degrader-27, enabling researchers to investigate the modulation of specific protein levels through ubiquitin-proteasome pathway engagement. Its application in chemical biology provides a valuable tool for studying protein function and regulation in various cellular contexts.
Product Information
Catalog NumA80222
FormulaC37H45FN4O7S
Molecular Weight708.84
CAS Number2375564-59-1
SMILESO=C(N[C@H](C(N1[C@H](C(NCC2=C(OCCC3=CC=C(C=C3)C4OCCO4)C=C(C=C2)C5=C(N=CS5)C)=O)C[C@@H](O)C1)=O)C(C)(C)C)C6(F)CC6
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