E3 Ligase Ligand-Linker Conjugate 91 is a conjugate composed of an E3 ligase ligand and a linker, featuring (S,R,S)-AHPC, a von Hippel-Lindau (VHL) ligand that effectively recruits VHL proteins. This compound serves as a crucial intermediate in the development of complete PROTAC (proteolysis-targeting chimera) molecules, enabling targeted protein degradation. Its application is significant in the exploration of innovative therapeutic strategies within chemical biology and drug discovery.
E3 Ligase Ligand-Linker Conjugate 91 is a conjugate composed of an E3 ligase ligand and a linker, featuring (S,R,S)-AHPC, a von Hippel-Lindau (VHL) ligand that effectively recruits VHL proteins. This compound serves as a crucial intermediate in the development of complete PROTAC (proteolysis-targeting chimera) molecules, enabling targeted protein degradation. Its application is significant in the exploration of innovative therapeutic strategies within chemical biology and drug discovery.
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